Alexey MOSKALEV, Insilico biomarkers and interventions in aging, EHA 2018

The Healthy Life Extension Society: https://heales.org Follow us on Twitter : https://twitter.com/_LongLongLife_ Follow us on Facebook : https://www.facebook.com/longlonglifedotorg/ Follow us on Linkedin : https://www.linkedin.com/company/22311577 Our Website : http://www.longlonglife.org The Eurosymposium on Healthy Ageing (EHA) meeting for 3 days in Brussels proclaims the possibility and the imperative of a moonshot project to overcome all age-related diseases within 25 years by tackling aging as their root cause. The world has already faced the variety of challenges caused by an ageing population and the so called "Silver tsunami", but Following major discoveries in science and biomedicine in recent years we are now on the edge of a paradigm shift from treatment to prevention and an improvement in healthy longevity. The defeat of aging lies within our collective grasp. It’s time to seize this remarkable opportunity ! Day 2 DNA damage and repair Alexey Moskalev Insilico biomarkers and interventions in aging A massive shift in the aging segment population will have major social and economic consequences around the world. One way to offset this increase is to expedite the development of geroprotectors, substances that slow aging and extend lifespan, of healthspan. GeroScope is a computational tool that can aid prediction of novel geroprotectors from existing human gene expression data. We shortlisted ten substances, all of which have lifespan-extending effects in animal models, and tested 6 of them for geroprotective effects in senescent human fibroblast cultures.

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